The splenocyte proliferation activity upon mitogen was suppressed by CPGS and RPGS, while the NK cell’s tumor-killing ability was promoted by CPGS. Results showed that CPGS and RPGS displayed diverse effects on the lymphocyte activity in the spleen. lucidum spores (RPGS) for 30 days to investigate their effect on the adaptive immune system. lucidum spores (CPGS) and the refined polysaccharides of G. In the present study, BALB/c mice ( n = 8–10) were administered with crude polysaccharides of G. Ganoderma lucidum (Leyss.Fr.) Karst is one of the well-known medicinal macrofungi all over the world, and mounting researches have focused on the polysaccharides derived from the spores of G.
